AMYLODIDOSIS
AMYLOIDOSIS Amyloidosis is the term used for a group of Fibrillar insoluble proteinaseous substance called amyloid having common morphological appearance, staining properties and physical structure but with variable protein composition (20-30 different proteins). ⚛ Production of abnormal amount of proteins  ⚛Production of normal amount of mutant production 🔹 Stimulus ➡ Soluble precursor ➡ Insoluble fibrils 🔹 Mutation ➡ Mutant Tranthretin ➡ ATTR Protein