ISCHAEMIC HEART DISEASE
ISCHAEMIC HEART DISEASE 🔸 Etiology 1) Coronary atherosclerosis 2) Complications in atherosclerotic plaque 3) Non-atherosclerotic causes 🔸 Etiology ⭕ Coronary atherosclerosis a) Distribution b) Location ⭕Complications in atherosclerotic plaque a) Ulceration b) Thrombosis c) Haemorrhage and plaque dyslocation ⭕ Non-atherosclerotic causes a) Vasospasm b) Stenosis of coronary ostia c) Arteritis d) Embolism e) Thrombotic f) Trauma g) Aneurysm 🔸 Effects of myocardial ischaemia a) Asymptomatic state b) Angina pectoris c) Acute myocardial infarction d) Chronic ischaemic heart disease/Ischaemic cardiomyopathy/Myocardial fibrosis. 🔸 Acute myocardial infarction (AMI) - 10 to 25% of all deaths - common in males - usually seen in elderly - less common below 40 yrs age - risk factors for atherosclerosis like hypertension - diabetes mellitus, cigarette smoking, familial hyperlipidemia etc increase chances of AMI. 🔸 Etiopathogenesis – Various factors individually or more co