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Showing posts with the label laboratory investigation

BLEEDING DISORDER

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BLEEDING DISORDERS If process of CLOTTING MECHANISM is known properly, very easy to diagnose the case and to treat to some extent.  ✴ Mechanism of action ✴ Laboratory investigations ▶Complete blood counts with peripheral smear examination  ▶ Screening tests for bleeding disorders ▶ Specific tests for factor deficiencies ▶ Platelet function tests  ▶ Other investigations as per requirements ✴ Screening tests for bleeding disorders ▶ Bleeding time, Clotting time ▶ Platelet Count ▶ Prothrombin time with INR (PT) ▶ Activated Partial Thromboplastin Time (aPTT) ▶ Thrombin time test (TT) ▶ Fibrinogen concentration ▶ F D P ✴Causes of bleeding disorders 1. Vascular defects 2. Platelet defects 3. Clotting mechanism defects 1. Acquired vascular defects 2. Congenital vascular defects